N-acetylcysteine (NAC) is the additional form of the amino acid cysteine. The supplement helps facilitate essential biological functions by combining with two other amino acids – glutamine and glycine – to form a powerful antioxidant called glutathione.
Why NAC supplements? N-acetylcysteine (NAC) as a food supplement is an antioxidant widely used in vivo and in vitro. It acts directly as a scavenger of radicals, in particular, oxygen radicals. It is also recommended as a possible treatment option for various disorders caused by the formation of oxygen free radicals.
Also, it is a long-lasting protected mucolytic drug that reduces stubborn mucus secretions. It has been used to treat various diseases in direct action or in combination with other drugs. It is a brilliant biohacking supplement too.
To help you find a good product, we have researched and found the Best N-Acetylcysteine Supplements currently on the market.
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NAC is an excellent source of sulfhydryl groups. NAC averts apoptosis and oxygen-related genotoxicity in endothelial cells, increasing intracellular glutathione levels and decreasing depolarization of the mitochondrial membrane.
Studies have shown no harmful effects on the mother or fetus in the treatment of NAC. NAC combination with vitamin E, or vitamins A+E, as well as essential fatty acids considerably, reduce reactive oxygen species (ROS), leading to pregnancy rate improvement. Studies have indicated that preserving the impact of NAC against the toxicity of chemicals is due to its dual role as a nucleophile and as a -SH donor.
The supplements we chose to compile our list can work as short-cuts to get these amazing benefits. Let’s take a look at their details!
NOW Foods NAC
Why We Picked It: High quality, highly rated by users and good for many people
NOW Foods NAC provides excellent free radical protection and antioxidant properties. Miscible with selenium and molybdenum. They can also cause some side effects for users and patients, so it is recommended that you consult a doctor before use to protect yourself.
Maintain healthy body cells and plywood with added sugar, salt, yeast, wheat, gluten, soy, leche, dairy, or shellfish. N-A-C supports tissue health by maintaining glutathione levels in the liver and increasing oxygen supply to liver cells. The addition of molybdenum and secretions is important for the production of some important enzymes in the body.
It contains N-acetylcysteine (NAC), which is a stable form of the amino acid L-cysteine. It contains sulfur, which helps stabilize the production of protein structures and the production of glutathione. 1 capsule twice a day should be taken. Sometime after opening the package, a black dot may appear, but the product is safe to use.
Highlights:
- 1000mg of NAC
- 120 tablets
- Soy-free
- Nut-free
- Gluten-free
- Non-GMO
Who Makes It?
This product is manufactured by NOW Foods, a leading global manufacturer of nutritional and natural supplements. With many years of experience, NOW is the undisputed industry leader that consistently produces high-quality products at very affordable prices. They are also famous for their excellent customer service. Since 1968, NOW has been manufacturing natural health products and supplements, and quality has always been the cornerstone of their business. Their mission as a business is to ensure the value of products and services that enable people to lead healthier lifestyles, and they fulfill this mission by consistently producing the highest quality natural products that complement any fashion of healthy living.
Pros:
- Helps with OCD and Anxiety
- Reduces depressive moods and improves your creative ability
- Beneficial for people suffering from Parkinson’s disease
- Help reduce asthmatic symptoms
- Boosts up sex drive
- Very beneficial for post-nasal drip
Cons:
- Better to avoid in case of bleeding problems
Swanson N-Acetyl Cysteine
Why We Picked It: Respected Manufacturer
As a powerful amino acid antioxidant, Swanson NAC (N-Acetylcysteine) is an important weapon in the war against free radicals and provides 600 mg of NAC per capsule. NAC helps to supplement glutathione, an integral part of the body’s immune system. Supports liver health and more. It contains a powerful antioxidant that supports the health of the liver and detoxification routes. It promotes the detoxification of toxins and environmental pollutants. It also supports healthy respiratory function and cellular antioxidant activity.
Highlights:
- 600 mg of NAC
- 100 capsules
- Other ingredients include gelatin and magnesium stearate
- The endorsed dosage is 1 capsule per day with water
- Money-back guarantee
Who Makes It?
This product is manufactured by Swanson Health Products (SHP), a catalog of health products and online marketing. The company sells natural products for health and well-being, including healthy foods, nutritional supplements such as vitamins, minerals, herbs, and natural personal care products, directly to consumers through directories by mail and on the e-commerce site. Swanson Health Products is the largest private seller of vitamins in the United States and one of Fargo’s most important employers with an estimated 250 employees.
Pros:
- Fights free radicals that can cause oxidative stress issues.
- Supports detoxification of environmental toxins and pollutants.
- Supports healthy respiratory function.
- Lowers Estrogen in women and men
- Helpful for trichotillomania
- Great for Vocal Tics TS
Cons:
- Sometimes it can cause diarrhea.
BulkSupplements Pure NAC Powder
Why We Picked It: Great Quality and Goodwill of The Company
Bulk Supplement Pure NAC is a good and pure product without any form of filler. It has been tested in the laboratory and tested for guaranteed quality. It does not contain a mixture of magnesium stearate and offers support for the proper functioning of the liver. NAC is not produced by the body and must be supplemented. The supplement contains N-acetyl cysteine, a sulfur-containing amino acid that is required for the synthesis of glutathione. Glutathione is a powerful antioxidant that is useful for removing harmful free radicals from the body. Cysteine accelerates the sulfate cycle and contributes to the overall detoxification of the body and reduces stress.
This product is soluble in water and tastes slightly acidic by nature. It can be mixed with water or juice to dilute the taste. As a dietary supplement, 600 mg (slightly less than ¼ teaspoon) should be taken up to three times a day as directed by the doctor. Bulk supplements Pure NAC Powder acts as an antioxidant and fights free radical damage that leads to signs of aging and disease. Research also suggests that it requires inflammation, especially after exercise, making it beneficial for training recovery.
This powdered form of NAC makes the supplement more bioavailable, which means that the body immediately begins to digest and absorb it. This supplement is sometimes taken with vitamin B6, vitamin E and a selenium supplement to further promote absorption and effectiveness.
Highlights:
- 600 mg of NAC
- The recommended dosage is 600 mg (about ¼ of a teaspoon) per serving
- 1 to 3 servings times per day
- No sugar, soy, or yeast
- Gluten and dairy free
Who Makes It?
This particular product is manufactured by Bulk Supplements, located in Henderson, Nevada. Bulk Supplements supplies over 400 pure nutritional supplements to hundreds of thousands of consumers and manufacturers. Bulk Supplements is dedicated to ensuring compliance with all sanitary standards. Each supplement is tested in its own laboratory before distribution so that all products are safe for consumption. For any additional tests, they use reputable and trusted independent laboratories in the USA.
Pros:
- Migrates effects of depression
- Great motivation booster
- Enhances the levels of glutathione in your body
- Good taste/smell
- Reverses the development of non-alcoholic fatty liver and helps in the body’s recovery after workouts.
- Puts an end to allergic reactions
Cons:
- Unattractive packaging
Jarrow Formulas N-A-C
Why We Picked It: Good For People With Sinus and Asthma
The Jarrow N-A-C (N-Acetyl-L-Cysteine) formula is a stable form of the amino acid L-cysteine. N-A-C is a cysteine that has been modified by the acetyl group, which has been stabilized and is becoming more biologically available.
In fact, this is a combination of cysteine and acetic acid, which are the main components of vinegar, L-cysteine, such as cysteine and taurine, are sulfur-containing amino acids that can be manufactured by the body from the important amino acid methionine. For this reason, this is considered an essential amino acid but is needed conditionally for infants, as well as in cases of certain nutritional deficiencies or debilitating conditions.
Lack of methionine in food, low selenium intake, chronic diseases, and old age reduce the body’s ability to convert methionine to cysteine. Similarly, stress and environmental toxins can increase the need for cysteine beyond the body’s ability to change. N-A-C is preferred over cysteine or cysteine as an additive because of its stability, solubility and greater ability to provide sulfur.
Jarrow Formulas N-A-C version of the continuous release supplement comes with fast delivery and continuous release. It supplies the body with more regular and continuous levels of L-cysteine for hours, day and night. N-A-C Sustain is a fast two-layer and sustained release formula for N-A-C. It raises blood levels and also maintains levels. Prolonged-release of SUSTAIN N-A-C in the small intestine and this increases the antioxidant effect of N-A-C for more than the standard N-A-C semi-periodic natural antioxidant in the blood.
Highlights:
- 500 mg of NAC
- 100 bilayer tablets
- Patented formula
- Other ingredients include carbomer, cellulose, calcium phosphate, beetroot powder, which add color, stearic acid, magnesium stearate, and silicon dioxide
- Gluten-free
- Soy-free
- Nut-free
- Shellfish free
Who Makes It?
This special product is produced by Jarrow Formula, based in Los Angeles, California, USA. It is a developer and supplier of high-quality nutritional supplements. The company was founded in 1977 and registered in 1988. It currently manufactures its products in the US, Mexico, Canada and throughout the world.
The mission of Jarrow Formula is reflected in the motto “Nutrition and Excellent Recipes.” Jarrow Formulas’ complete food line includes vitamins, minerals, probiotics, standardized plant concentrates, amino acids, enzymes, and enteral nutritional products. The company is actively involved in government regulatory issues affecting the food industry. It also actively promotes the right of Americans to free food supplements.
Pros:
- Minimizes sinus congestion during cold and allergy season.
- Great for asthmatic patients as it improves breathing.
- Neutralizes acetaminophen poisoning.
- It doesn’t result in stomach upset.
- This improves the level in the blood and as well maintains the levels.
- Helps with brain fog
- Metformin alternative for PCOS
Cons:
- May result in stomach upset
- Bad taste.
Source Naturals N-Acetyl Cysteine
Why We Picked It: High Quality and Dose
Source Naturals NAC is a more stable form of the amino acid L-cysteine and is a strong precursor of cysteine and glutathione. Glutathione is a major antioxidant as a cofactor for glutathione peroxidase, one of the most important enzymes in the body. In addition, a meta-analysis of human clinical trials has shown that supplementation with N-acetylcysteine supports respiratory health.
Source Naturals NAC is not recommended if nitrate formulations such as nitroglycerin are used. If someone is pregnant, may be pregnant or breastfeeding, they should consult their health care provider before using this product. Does not contain yeast, milk products, eggs, gluten, corn, soy or wheat. Does not contain sugar, starch, preservatives or artificial colors, flavors or flavors.
Highlights:
- 1000 mg of NAC
- 42 mg of calcium
- Found in 30, 60 and 120 tablets bottles
- Dairy-free
- Gluten-free
- No artificial colors, flavors or fragrances
- No salt or other preservatives
- Non-active ingredients include dibasic calcium phosphate, stearic acid, microcrystalline cellulose, colloidal silicon dioxide, modified cellulose gum, and magnesium stearate.
Who Makes It?
This special product is manufactured by Source Naturals, which then introduces an award-winning formula that is recognized for its excellence in independent research and nutrition analysis. Their nutritional supplements are at the forefront of the modern healthcare revolution. This transformation in health awareness also includes new perspectives on diet, lifestyle, emotional and spiritual development, and additional medical care.
Pros:
- Improves asthma.
- Improves the frequency of infections.
- It helps with inflammatory issues.
- An amazing supplement for liver supports as well as anti-depression properties.
- Works as a big help with skin picking disorder.
- Works as an antidepressant
Cons:
- Smells bad.
Nutricost N-Acetyl L-Cysteine
Why We Picked It: High Quality and Good Reputation
Nutricost N-Acetyl-L-Cysteine is a stable form of the cysteine essential amino acid. This is an amino acid containing sulfur which acts as a stabilizer for the formation of protein structures. Features include 600 mg of high-quality NAC per capsule, 180 capsules per bottle, non-GMO, gluten-free, tested by third parties. It was made at a registered FDA facility that met GMP requirements.
Nutricost N-Acetyl L-Cysteine limits alcohol damage to the liver (if used before use); it is a powerful antioxidant; this is good for acne, shows the prospect of reducing the toxicity of drugs for ADHD; promising in the treatment of nicotine (and other stimulants) addictions.
Highlights:
- 600 mg of NAC
- 180 capsules per bottle
- Made in the USA
- Other ingredients include gelatin and rice flour
- Non-GMO
Who Makes It?
This special product is produced by Nutricost (nutricost.com), which is a smaller group of supplements and vitamins that compete with other supplement brands. Their motto is to keep prices low and competitive. Their motto also defines its impressive warranty details. Guarantees that allow customers to see for 60 days how this supplement can affect their lives.
Pros:
- It helps with compulsive behaviors.
- It helps with COPD.
- It helps to break up mucus.
- Directly reduces NAPQI
- Increases sulfonation
- Helps with colorectal distress immediately
Cons:
- Horrible smell and taste.
- A strong smell of ammonia.
Thorne Research N-Acetyl Cysteine (NAC)
Why We Picked It: Good For Liver Diseases
Thorne Research N-Acetyl Cysteine (NAC) is known for its ability to detoxify the liver due to its antioxidant activity. It improves respiratory health by increasing mucus thickness. This increases the level of glutathione, which is the main antioxidant that detoxifies the body.
Thorne Supplements are made from natural and pure ingredients throughout the world. It contains flavors, colorings, preservatives, and sweeteners derived from natural sources. It’s gluten-free and not GMO. It does not contain artificial preservatives or allergic substances such as wheat, rye, oats, eggs, nuts, dairy products, soybeans, corn, and yeast. It does not contain sugar or magnesium.
Highlights:
- 500 mg of NAC
- 90 capsules
- Other elements include hypromellose, which is taken from cellulose, leucine and silicon dioxide.
- Capsules are vegetarian
- The recommended dose is 1 capsule two to three times per day
Who Makes It?
This specialty product is manufactured by Thorne Research, a food supplement company. The company supplies blood circulation, cognitive, detoxification, endocrine, and other essential medical products. They believe that good health can always be improved. Because no one should be limited to a definition of health that is not optimal. They offer personalized home tests to help people understand their health and supplements to reach their full potential.
Pros:
- Boosts liver health
- Assuage sinus congestion
- Boosts liver support
- Enhances the immune system
- Minimal binder or filler content
- Helps with CNS Burnout
Cons:
- Can result in diarrhea
Life Extension N-Acetyl Cysteine
Why We Picked It: Good For Chronic Bronchitis Patients
Life Extension N-Acetylcysteine is known for its ability to detoxify the liver due to its antioxidant activity. It promotes healthy breathing by increasing the thickness of mucus. It increases the level of glutathione, which is the main antioxidant that leads to detoxification of the body.
The NAC Life Extension increases the level of cellular glutathione around it and is generally not GMO LE certified.
Highlights:
- 600 mg of NAC
- 60 vegetarian capsules
- Dairy-free
- Nuts-free
- Shellfish free
- Gluten-free
- Contains no sugar, artificial sweeteners or preservatives
- Other elements include gelatin, vegetable stearate, and silica
- Take 1 capsule 1 to 3 times every day
- Drink 6 to 8 glasses of water everyday when taking the supplement to avoid the creation of kidney stones.
Who Makes It?
This special product is produced by the Life Extension Foundation, a company that sells supplements and vitamins. The stated goal is to extend the life of healthy people by finding methods to combat aging and eradicate disease.
Pros:
- Helps with excoriation (obsessive skin-picking) disorder.
- Great for joints and for bones aches due to arthritis.
- Great for people with chronic bronchitis.
- Helps in fighting asthma
- Women with lipedema should use it
- Helps to breathe better
Cons:
- None.
Best Naturals NAC N-Acetyl L-Cysteine
Why We Picked It: Great Value and Quality
Best Naturals NAC is a stable form of the essential amino acid L-cysteine. It is a sulfur containing amino acid that acts as a stabilizer for the formation of protein structures, and is also necessary for the formation of glutathione, which provides various protective effects, including detoxification and intracellular protection against oxidative stress.
Best Naturals NAC has no artificial colors, flavors or sweeteners. It supports healthy liver function, healthy lung function, cell health, and glutathione synthesis.
Highlights:
- 600 mg of NAC
- 250 capsules per bottle
- Made in the USA
- Purity and potency are guaranteed
- Meets GMP standards
- Other elements include gelatin, silica and vegetable stearate
- The suggested dosage is 1 capsule one to three times everyday on an empty stomach with fruit juice
- No artificial colors, fragrances.
Who Makes it?
This certain product is manufactured by Best Naturals, which is a company that manufactures supplements. This was the best natural product, the company producing the additives. It was established with love and desire to provide high quality dietary supplements. Today, the brand is highly credited with the best natural nutrition products to provide the best assistance.
Pros:
- Helps with blood sugar
- Very important for immune health
- Helps with IPF (Idiopathic Pulmonary Fibrosis)
- Mitigates the effects of alcohol if taken before drinking it
- Helps greatly in combating infection
- Beneficial in case of warding off cold
Cons:
- Bad odor
Benefits of NAC
As an antidote to Nac-acetaminophen poisoning, many are used through knowledge of defense machinery. NAC is a precursor of glutathione, increasing the concentration of available glutathione starting from non-English APAP, which acts as an anti-inflammatory and free-hocsaideach and inotropic and positive.
- Necessary for the powerful antioxidant to make Glutathione: In addition to the other two amino acids – glutamine and glycine – NAC glutathione, or any other action is needed. Glutathione is one of the most important antioxidants in the body, which causes the next day to neutralize the damage from free radicals to the body’s cells and tissues. To deal with many other diseases and antioxidant properties and the importance of oxidizing stress such as heart disease, infertility and some psychiatric conditions.
- Improving Psychiatric Disorders and Addictive Behavior: NAC helps regulate glutamate levels – the most important neurotransmitter in the brain. For people with bipolar disorder and depression, NAC can help reduce symptoms of improving exercise potential. What’s more, research suggests that they may have a role to play in the treatment of moderate to severe OCD.
- Helps reduce symptoms of respiratory conditions: NAC can relieve symptoms of respiratory conditions by acting as an antioxidant and eye, releasing mucus in the airways. As an antioxidant, NAC helps restore the levels of glutathione in the lungs and reduces inflammation in the bronchial tube and lung tissue.
Side Effects of NAC
- When taken orally: N-acetylcysteine is probably safe for most adults. This can cause nausea, vomiting, and diarrhea or constipation. Rarely, it can cause skin rash, fever, headache, drowsiness, low blood pressure, and liver problems. N-acetylcysteine has an unpleasant odor that makes absorption difficult.
- When administered intravenously: N-acetylcysteine is PROBABLY SAFE for most adults when given intravenously as a prescription. Rarely, it can cause skin rash, fever, headache, drowsiness, low blood pressure, and liver problems.
- Asthma: There is concern that N-acetylcysteine may cause bronchospasm in people with asthma by inhalation or ingestion or through a tube in the trachea. If you are taking N-acetylcysteine and you have asthma, you should consult your doctor.
- Pregnancy or breastfeeding: N-acetylcysteine is POSSIBLE SAFE when administered orally, administered through an opening in the trachea, or inhaled by pregnant women. N-acetylcysteine crosses the placenta, but there is no evidence that it harms the fetus or mother. But N-acetylcysteine should only be used in pregnant women when clinically necessary.
- Hemorrhagic disorder: N-acetylcysteine may decrease blood coagulation. There is concern that N-acetylcysteine may increase the risk of bruising and bleeding in people with bleeding disorders.
Who Should Take NAC Supplements
You should only consider taking NAC supplements if you belong to any of the following categories:
- People who are prone to flu and cold
- People with hepatitis C
- People who are suffering from liver problems
- People with OCD
But before starting to take the supplements, be sure to consult your doctor.
How to Take NAC Supplements
Look for NAC in capsules and tablets, alone or in combination with antioxidants, herbs, and other immune-supportive ingredients.
Different people have different reasons to take NAC supplements, and the dosage varies depending on the reason. Here are the recommended dosages:
- Flu Prevention: 600 mg twice a day during flu season
- Hepatitis C: 1000 mg divided into doses.
- Liver Cleans: 500-600 mg daily
- OCD: 600 mg two to four times
How to Choose a Good NAC Supplement
While choosing a NAC supplement, you should definitely consider a few benchmarks. Otherwise you might receive more harms than benefits for choosing the wrong product. These are the things you should consider:
- Amount of NAC per serving: Too high of an NAC dosage can cause serious trouble to your body. Depending on your doctor’s advice, choose the right amount of NAC per serving.
- Reputation of manufacturer: As NAC supplements have become quite popular lately, lots of makeshift companies are trying to enter the market. You should only purchase products from manufacturers with a good reputation. Research about the manufacturer before making a purchase.
- Additives: Many supplements come with additives, be sure to avoid them.
- Added ingredients: Apart from the core ingredients, some supplements add other nutrient elements. Have a look at the ingredient list on the packaging to avoid allergens.
- User reviews: And last but not the least, see what other users have said about the product.
NAC Supplement FAQs
Q: What is NAC good for?
A: Fighting acetaminophen poisoning: High doses of acetaminophen or chronic use at lower doses can impair the liver’s ability to produce glutathione, resulting in liver failure and death. NAC restores normal levels of glutathione in the liver and helps to heal liver damage caused by acetaminophen.
Protection against colds and flu: According to an Italian study of the elderly, NAC supplements can block influenza syndromes.
Polycystic Ovary Syndrome (PCOS): In a recent study, doctors found that moderately high doses of NAC lead to improvement in women with PCOS.
Q: When Should One Take NAC?
A: NAC should be taken either 30 minutes before, or two hours after, eating to avoid competing with protein absorption.
Q: How Much NAC One Should Take Per Day?
A: Daily intake of NAC should be somewhere between 600-1800 mg.
Q: Is It Necessary to Take NAC Every day?
A: No, NAC is not an essential nutrient, so you are not bound to take it every day.
Final Thought
N-acetylcysteine is an effective medication for acetaminophen overdose and mucous breakdown. Cancer treatment has not been proven. NAC is a natural compound in the body. It becomes glutathione, a chemical whose role is to detoxify foreign bodies in the body. It is used as an antidote for acetaminophen overdose.
NAC itself is an antioxidant that neutralizes free radicals that damage DNA. NAC can dissolve and secrete mucus in patients with respiratory diseases, such as chronic bronchitis and chronic lung disease (COPD), but the test results are varied. Animal studies also show that it can protect tissues from drugs like doxorubicin, ifosfamide, and cyclophosphamide. These effects are currently being studied in humans. NAC regulates glutamate levels in the brain. It has been examined for a range of mental disorders in people with limited access.
