Product Reviews

Best P-Synephrine Supplements in 2023

P-Synephrine is an alkaloid, which means it’s an organic compound that can be found in nature and has nitrogen as a base. P-synephrine dietary supplements are predominantly known for being effective in terms of weight loss or management and sports performance.

Why P-Synephrine supplements? P-synephrine can naturally be found in lots of citrus fruits—like oranges, mandarins, and grapefruits, but the quantity and concentration is very low. That’s why, a suitable P-synephrine supplement can be a great addition to your diet. P-Synephrine is particularly abundant in the bitter orange fruit, which is why it’s often referred to by that name. Biohackers also use P-synephrine supplements. 

Here we picked the Best P-Synephrine Supplements for you to choose from:

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These supplements will make sure you get enough amount of P-Synephrine to reduce body fat or modify body composition. It will bolster your weight loss journey and help you remain fit. So, here is a list of supplements containing P-synephrine that you can use alone or in combination with a diet and/or physical exercise.

There are several benefits to each of the p-Synephrine supplements that we are recommending for you. We are providing you with proper descriptions of all the good p-Synephrine supplements instead of simply giving you a top 10 list. This way, you can choose the perfect supplement for you based on your needs and lifestyle. So, keep on reading to find out which p-Synephrine supplement is the most suitable one for you and also avoid any probable side-effects.

Now let’s take a look at the supplements we have chosen for our list.

NutriCargo Bitter Orange Powder

NutriCargo Bitter Orange Powder

Why we picked it: Customizable dose and effective formula.

NutriCargo Bitter Orange Powder is a bulk package of pure bitter orange powder that contains no other ingredients or preservatives. It is an effective P-Synephrine supplement but the powder needs to be mixed into water or food or put into capsules. 

Highlights: 

  • The package contains 1kg (2.2 pounds) of a pure bitter orange powder 
  • The dosage can be customized according to preference 
  • No other ingredients or additives
  • You can mix the powder into water/food, or put in empty capsules
  • Ethically Harvested
  • Each order is hand picked and packaged to ensure freshness and quality

Who Makes It:

NutriCargo is a New Jersey based wholesale supplier of health ingredients. They sell wholesale, bulk packages of raw tropical or green ingredients, different types of powders and extracts. Nutricargo supplies their ingredients to other supplement manufacturers as well as their own customers.

Pros:

  • All natural ingredients from all over the world
  • Convenient bulk amount 
  • Does not contain additives
  • Can be customized into a shake, food or even taken as a capsule.

Cons:

  • The plastic bag causes inconvenience when you try to reseal it after every use.

TerraVita Bitter Orange Extract

TerraVita Bitter Orange Extract

Why we picked it: Doses can be customized, made with 100% natural ingredients 

TerraVita bitter orange extract is a strong, effective supplement containing 10% P-Synephrine. It is a powdered bitter orange product that’s sold in bulk packaging instead of capsules. This means TerraVita bitter orange powder is a bit less convenient than capsules as you’ll need to measure out your own doses.

Highlights: 

  • The product contains 10% P-Synephrine
  • Can be mixed with water and taken with regular meals
  • 100% natural ingredients
  • The dosage can be customized according to your preference 
  • Bulk- packaging
  • Less convenient than capsules
  • Does not contain preservatives or unnecessary additives

Who Makes It:

TerraVitta is a manufacturer of vitamins, health supplements and teas. TerraVita’s mandate is to manufacture products using the highest standards of potency, purity, freshness and stability. All TerraVita products are distributed worldwide.

Pros:

  • Great in purity, strength and effectiveness
  • Customizable dosage
  • Natural ingredients can support congestion and indigestion
  • Can be made into shakes for better consumption 
  • No unnecessary additives

Cons:

  • Less convenient than capsules as you’ll need to measure out your own doses.

Earth Natural Supplements Bitter Orange Extract 

Earth Natural Supplements Bitter Orange Extract

Why we picked it: Provides strong dose, 100% natural and additive free

Earth Natural Supplements is a powerful P-Synephrine supplement with 500mg per serving that contains 6% P-Synephrine. It’s 100% natural and additive-free. This is a good product for those looking for a strong dose of P-Synephrine. It is made by a trustworthy company in the USA. 

Highlights: 

  • 500mg bitter orange per serving
  • 6% P-Synephrine
  • 100% natural
  • Soy-free, Dairy-free
  • Contains gelatin and rice powder
  • Does not contain any artificial coloring, flavor or preservatives 
  • Made in the USA

Who Makes It:

Earth Natural Supplements manufactures quality nutritional supplements and vitamins with natural ingredients to improve the health of consumers. 

It is a US-based supplement company that sells their products online. 

Pros:

  • A powerful P-Synephrine supplement with good reviews 
  • Avoids all major allergens such as soy, dairy etc
  • Manufactured with natural ingredients 
  • US- made and additive- free

Cons:

  • Contains gelatin and isn’t Vegan/ Vegetarian-friendly

Primaforce Syneburn 

Primaforce Syneburn

Why we picked it: Pure form of P-Synephrine, manufactured by a reputed company

Primaforce Syneburn is a bitter orange supplement that contains a concentrated dose of P-Synephrine. It is an effective weight loss supplement designed to increase metabolism and burn fat. This product is manufactured by a well-known company, but it has rather average customer reviews.

Highlights: 

  • 10mg P-Synephrine per serving
  • Each bottle contains 180 capsules
  • Contains pure and concentrated dose of P-Synephrine 
  • Produced in a GMP-compliant facility
  • Manufactured by high quality ingredients 
  • Average reviews

Who Makes It:

PrimaForce is a supplement company that manufactures products for weightlifters, bodybuilders and athletes. The company provides its consumers with high-quality products to enhance performance, body composition, and quality of life. They use only pharmaceutical-grade, clinically-tested ingredients to make their products. 

Pros:

  • Made with High quality ingredients in a cGMP facility 
  • Lab-tested for potency and purity
  • Provides a concentrated dose of 10mg P-Synephrine per serving
  • Increases resting metabolic rate which can enhance weight loss.
  • Works as a great fat-burner

Cons:

  • The product only has mediocre reviews from the consumers.  

NusaPure Bitter Orange

NusaPure Bitter Orange

Why we picked it: 100%Vegetarian Capsules, pure extract with a maximum strength formula

NusaPure Bitter Orange is a 500mg P-synephrine supplement that is Vegetarian, Non-GMO & Gluten Free. It is highly effective as a weight loss supplement and also works well as a natural appetite suppressant.

Highlights: 

  • Manufactured with 100% vegetarian friendly ingredients 
  • One bottle of product contains 180 capsules
  • 500mg pure high potency maximum strength bitter orange in every capsule. 
  • Premium quality P-Synephrine supplement 
  • Made in the USA 
  • Absolutely dairy-free, gluten and soy free
  • Manufactured in FDA inspected and GMP certified facilities
  • Great reviews

Who Makes It:

Nusapure is a company in the United States that manufactures products with all natural, high quality, herbal formulas to treat common health issues. All their nutritional supplements and health products are organic and made with proper research in non-GMO facilities. 

Pros:

  • Only organic and natural items are used in the creation of this product.
  • 100% Vegetarian Capsules that are easy to swallow and odorless 
  • Pure extract with a maximum strength formula 
  • NusaPure is a trusted brand – recognized by Amazon for excellent customer service
  • Made in the USA, in FDA inspected and GMP certified facilities
  • The P-synephrine contains no sugars, salts, starches, gluten, soy or milk 

Cons:

  • Can cause health problems if mixed with caffeine. 

Legion Phoenix Fat Burner

Legion Phoenix Fat Burner

Why we picked it: Contains ingredients that help lose fat faster and fight hunger.

Legion Phoenix Fat Burner is a 100% natural fat burner that speeds up your metabolism, enhances fat burning, and reduces hunger and cravings. It contains a clinically effective dosage of P-Synephrine, naringin, and hesperidin. If you want to lose fat faster without taking stimulants or other potentially harmful chemicals, this P-synephrine supplement is a good choice for you. 

Highlights: 

  • 100% natural caffeine-free fat burner
  • 5 capsules serving size
  • Contains 6% P-Synephrine 
  • Each bottle has 30 capsules
  • Soy free and Dairy free
  • Most effective if taken with caffeine 
  • Made in FDA inspected facility

Who Makes It:

Legion aims to create healthy, high-quality sport supplements based on sound science. This company is committed to creating supplement formulations that are 100% backed by peer-reviewed scientific research. Legion tries to provide a fantastic value and customer experience through their products.

Pros:

  • Natural and potent supplement at 6% P-Synephrine 
  • Made with quality ingredients in a FDA inspected facility ensuring great manufacturing process 
  • Doesn’t include major allergens like soy or dairy 
  • Caffeine- free and efficient at burning fat quickly

Cons:

  • Needs to be added with caffeine for maximum effectiveness which can cause health problems

Solaray Bitter Orange

Solaray Bitter Orange

Why we picked it: Top quality product made by a trustworthy company.

Solaray Bitter Orange is a top-quality P-Synephrine supplement containing 120mg of bitter orange extract (standard 6% P-Synephrine) in each serving. It is highly effective and manufactured by a company you can trust. This is one of the better bitter orange supplements out there. It contains an optimal dose, has no fillers or fluff and plenty of great reviews make the game product trust-worthy.

Highlights: 

  • 60 capsules per bottle
  • 120mg bitter orange extract per serving
  • Standardized to 6% P-Synephrine
  • Good reviews
  • Comes in a vegetable cellulose capsule
  • Contains no additives or fillers 
  • Manufactured by a leading brand

Who Makes It:

Solaray is the flagship brand of the health supplement manufacturer Nutraceutical Family of brands. They offer over 1,000 unique products and have built a worldwide reputation for consistency and quality in their creations. They provide a full line of supplements, herbal extracts, vitamins with functional formulas designed for today’s lifestyle.

Pros:

  • Provides an effective and strong dosage
  • Great reviews
  • Created with high quality ingredients 
  • Vegan and vegetarian friendly 
  • Free of any artificial fillers or additives

Cons:

  • Each capsule only contains 120mg so each bottle will not last for a long period of time

Naturetition Supplements Bitter Orange Extract

Naturetition Supplements Bitter Orange Extract

Why we picked it: Best in purity and strength, 100% natural

This is a strong P-Synephrine supplement that contains a strong dosage of 500mg per serving. It’s 100% natural, with no additives or unnecessary ingredients. The only other ingredients are gelatin and rice powder which help the capsules stay together. So, its effectiveness, purity and strength make it one of the best in the market.

Highlights: 

  • 500mg bitter orange per serving
  • Each bottle contains 90 capsules
  • Standardized to 6% P-Synephrine
  • 100% natural
  • Made in the USA
  • Great reviews
  • Contains no additional fillers 

Who Makes It:

Natureition supplements is a US based health supplement manufacturing company. They make pure and natural supplements and sell their products online on Amazon. Naturetition supplements is a small but growing company with good reviews from the consumers. 

Pros:

  • Great reviews
  • Does not contain any preservatives, artificial coloring
  • Soy and Gluten free
  • Made in the USA
  • 100% natural

Cons:

  • Not suitable for people who are strict vegetarians because it contains gelatin

Serene Dew Supplements Bitter Orange Extract

Serene Dew Supplements Bitter Orange Extract

Why we picked it: No additives and 100% natural product.

Serene Dew Supplements Bitter Orange Extract is a simple and effective P-Synephrine supplement with 500mg in each serving.This is a good product with no fillers or unnecessary ingredients. It’s 100% natural and gluten-free.

Highlights: 

  • 500mg bitter orange per serving
  • 6% P-synephrine
  • Each bottle has 90 gelatin capsules
  • 100% natural 
  • Gluten-free and dairy-free
  • The other ingredients consist of Gelatin and Rice Powder
  • Contains no Synthetic coloring, flavor or preservatives

Who Makes It:

Serene Dew Supplements is a company that specializes in manufacturing health products. Their primary focus is on creating innovative health products from natural ingredients that avoid all major allergens as well as any unnecessary additive or preservatives.

Pros:

  • Moderately strong P-Synephrine dosage
  • Made from 100% natural ingredients 
  • Gluten-free and Dairy-free
  • Avoids all major allergens
  • Does not contain artificial color, flavor or preservatives 

Cons: 

  • It has gelatin and hence not vegan/vegetarian- friendly 

PureControl Supplements Bitter Orange Extract

PureControl Supplements Bitter Orange Extract

Why we picked it: Strong and effective, doesn’t include additives or preservatives.

This is a strong P-synephrine supplement with 500mg bitter orange extract per serving. This is a good product, but not unique and can be easily replaced by any other alternative P-synephrine supplement. The product is produced by a third party and privately branded under the PureControl name.

Highlights:

  • The product had 6% P-Synephrine
  • 180 capsules in each container
  • 500mg bitter orange extract per serving
  • Made in the USA
  • No additives or preservatives
  • Pure and Natural ingredients used in the manufacturing process
  • Other Ingredients: Gelatin, Rice Powder.

Who Makes It:

This P-synephrine supplement is made by the company PureControl Supplements. It is an upcoming privately owned branding firm that does not manufacture products by itself. PureControl Supplement sells third-party manufactured supplements under their own name.

Pros:

  • Pure and Natural
  • Likely to last a long time with 180 capsules per container
  • Avoids all major allergens
  • Gluten, soy, dairy and sugar free
  • Contains no unnecessary additives 

Cons:

  • Produced by a third party which cannot guarantee high-quality 

Renevitol Bitter Orange Standardized Extract

Why we picked it: standard bitter orange extract containing P-Synephrine

Renevitol Bitter Orange Standardized Extract is a run-of-the-mill P-synephrine containing product. This is a simple supplement with 500mg bitter orange extract per serving. The product is manufactured by an unlisted third party and there’s nothing particularly unique about it. 

Highlights: 

  • 500mg per serving
  • Standardized to 6% P-Synephrine
  • 90 capsules in each container
  • Manufactured by a third party
  • The ingredients consist of gelatin, rice powder but no artificial coloring or flavor
  • Does not contain milk or milk derivatives, lactose, soy, sugar or gluten
  • Free of all major allergens

Who Makes It:

Renevitol Nutrition USA is a privately owned company. It is a branding company that sells products under the Renevitol name manufactured by an unlisted third-party. The company produces health supplements, bodybuilding supplements and other nutrients using natural ingredients.

Pros:

  • Manufactured with only natural ingredients like bitter orange extract, rice powder and gelatin
  • Simple formula with moderate amount of P-synephrine 
  • Does not consist of any additives, color, flavor
  • Soy- free, Gluten-free and dairy free

Cons:

  • Produced by an unlisted third party and not vegan- friendly

GLS Bitter Orange Standardized Extract

GLS Bitter Orange Standardized Extract

Why we picked it: Private branded and manufactured in the USA.

GLS Bitter Orange Standardized Extract

is a standard bitter orange product with a 500mg dose. This supplement is US-made but the manufacturing process is done by an unlisted third party. This is basically just another P-synephrine supplement without any special features but it avoids any additives or allergens

Highlights: 

  • Contains 6% P-Synephrine
  • Avoids all major allergens like milk or milk derivatives, soybean, gluten etc.
  • 500mg bitter orange extract per serving
  • Made in the USA
  • Private branded
  • No additional ingredients used

Who Makes It:

GLS nutrition is a privately owned branding company that makes glucose lowering supplements. It makes potent supplements with natural ingredients by a third party manufacturer that’s not listed and sells it under the GLS name.

Pros:

  • No additives, artificial color or flavor
  • Pure and potent dose of bitter orange extract containing P-synephrine
  • Gluten-free
  • Soy-free and dairy-free
  • Produced in a US based manufacturing facility

Cons:

  • No guarantee of quality due to third party manufacturing 

Benefits of the P-synephrine supplement

According to several researchers, P-synephrine is highly beneficial for weight loss and treating obesity, circulation, fatigue, digestion issues, and more. It can also reduce appetite, boost metabolism and improve fat oxidation, especially when taken in conjunction with stimulants like caffeine.Most of these claims have not been definitively confirmed in clinical trials, although bitter orange supplements containing P-Synephrine do show some interesting potential. Some uses include:

  • Weight loss and Obesity treatment: There’s a wealth of research and studies connecting synephrine and weight-loss. One clinical study claims synephrine alkaloids could help treat obesity and aid with weight-loss. Another indicates that the acute ingestion of P-Synephrine supplements can help increase fat oxidation and energy expenditure during workout.
  • Improve metabolism and Fat oxidization: Some studies have shown that P-Synephrine is similar to adrenergic agents. More specifically, it can help improve liver metabolism, increase glycogenolysis and enhance calorie burning to aid with weight reduction. On the other hand, P-Synephrine could help suppress glucose production.
  • Other health benefits: P-Synephrine can bring several other benefits that include reducing glucose production, improving heart health, minimizing nasal congestion and treating constipation. On top of that, some research has shown that topical bitter orange oil containing Synephrine can help treat fungal infections such as athlete’s foot, ringworm and jock itch.

How to take P-synephrine Supplements 

P-synephrine is a stimulant similar to caffeine and ephedrine so it can help burn fat, suppress appetite, and increase energy. It’s often taken as a weight management supplement to boost metabolism and reduce fat. Generally, it is consumed in a powder or capsule form. The powder form needs to be customized into a shake whereas the capsules made of gelatin or cellulose are a lot more convenient. P-Synephrine can also be taken with caffeine to optimize fat burning. 

There is no official recommended dosage for P-Synephrine supplements. It’s best to follow manufacturer instructions and consult with your doctor first. Most supplements contain around 500 mg bitter orange per serving. Some physicians recommend a dose of 10-20mg of pure synephrine per serving, up to 3 times per day. As most bitter orange extracts are standardized to 6% synephrine, a 500mg dose of bitter orange supplement would contain approximately 30 mg of synephrine.

Who Can Take P-synephrine Supplements

Only healthy adults 18 years of age should use the Bitter Orange products containing P-Synephrine. Your doctor can help you decide if the supplement has benefits that can enhance your life. However, children shouldn’t use Bitter Orange supplements. Pregnant women and Women who are breastfeeding should also avoid the use of P-synephrine supplements because it is unknown if there are any side effects in the infant.

Glaucoma sufferers should not use Bitter Orange as well. The P-synephrine supplement is known to worsen the condition. Evidence supports that it may interfere with blood sugar control. If you currently take prescription medications, it is best to speak to your doctor before using this supplement.

How to Pick a Good P-synephrine Supplement

A good P-synephrine supplement should be made by a reputable company. Since the supplement can cause some potentially serious side effects, many well-known brands no longer manufacture this product.

Finding a bitter orange supplement containing P-Synephrine made by a trustworthy company might be difficult. It should be manufactured in a non-GMO facility containing few to no unnecessary ingredients or fillers. 

Most bitter supplements will contain a standardized concentration of P-synephrine, the active ingredient. The concentration is typically between 6 and 10 percent. Since synephrine is the primary active ingredient, it’s important to consider this concentration.

Frequently Asked Questions About P-synephrine Supplements

Q. What side- effects can occur from P-synephrine supplement?

Answer: The P-synephrine supplement can cause a variety of health problems and side-effects. The chances of side-effects are increased when the supplement is used in combination with caffeine or supplements containing caffeine. Potential side effects include:

  • High blood pressure
  • Stroke
  • Fainting
  • Headaches and migraines
  • Sensitivity to light/the Sun 

So, consulting a doctor or health expert before starting the use of P-Synephrine supplements is highly recommended.

Q. Is P-synephrine a stimulant?

Answer: No, but it is often confused as a stimulant because of its structural similarity to other stimulants such as epinephrine, norepinephrine, and ephedrine. 

Q. Does P-synephrine give you energy?

Answer: No, as it doesn’t have effects on the cardiovascular system, it is not able to increase or boost energy levels. Some supplements have additional caffeine along with P-synephrine, but their mechanisms are entirely different. 

Final Thoughts

It’s evident that P-Synephrine, a chemical found in bitter orange or citrus aurantium, can assist with weight management and does have some health benefits. However, this substance appeared to be most effective for weight-loss and increased athletic performance when it is combined with stimulants such as caffeine.

Since there are certain side effects that can occur while using P-Synephrine, it’s best to fully understand the supplement, all of its ingredients, and your overall health before taking anything. It’s also wise to avoid taking too much of this ingredient. This should help you avoid adverse reactions.

If you have any pre-existing medical conditions or health problems, be sure to consult a licensed physician before taking any P-Synephrine supplements.

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