Product Reviews

Best Uridine Supplements in 2023 – And Why

Uridine, a nucleotide base found in high levels in beer, is used for increasing synthesis of cellular membranes and also appears to have potentially cognitive enhancing properties.

Uridine helps to synchronize several neural connections to the central nervous system and functions as mood changers. By taking the uridine supplement, improvements can be made to memory, relieve anxiety, and mental performance along with preserving and enhancing grey matter as one ages.

Uridine supplements reduce daydreaming, amnesia (uridine monophosphate anxiety), increase concentration and mood positivity, increase gray matter in the brain and improve spatial working memory. It is recommended to take uridine with food out of prudency, but this has not been noted to be an absolute requirement.

Few Of The Best Uridine Supplements On The Market At The Moment Are As Follows:

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Double Wood Uridine Monophosphate

Double Wood Uridine Monophosphate

Why We Like It? 

Improves working memory,upregulates dopamine receptors

As a supplement it improves working memory and slows the aging process in the brain. Double Wood Supplement’s Uridine is manufactured in New York city and is tested for purity right here in the USA.

Highlights:

  • 60 capsules per container
  • 300mg Capsules 
  • Gelatin capsules
  • Contains cellulose 
  • Contains magnesium stearate 
  • Made in the USA

Who Makes It?

Double Wood Supplements is a small business offering pure dietary supplements and nootropics to purchasers. They strive to provide only the highest quality of products at a reasonable price. All of their products are sourced from GMP certified FDA approved facilities and are manufactured within the US.

Pros:

  • Soy Free
  • Gluten Free
  • Non-GMO
  • Kosher
  • Supports cholinergic function
  • Supports brain health
  • Promotes synaptic connections

Cons:

  • Mild headaches, upset stomach, and nausea
  • Not recommended for pregnant women

NatureBell Uridine Monophosphate

NatureBell Uridine Monophosphate

Why We Like It?

Maximum Strength Uridine Capsules, adrenal support 

The maximum strength uridine promotes and supports cognitive function and health along with improving concentration and mental focus. 

Highlights:

  • Uridine 350mg 
  • 60 Capsules per container 
  • Contains Magnesium Stearate
  • Active ingredients include choline 
  • 3rd Party Lab Tested and Made in California

Who Makes It?

NatureBell premium grade supplements are produced from the finest quality raw materials from around the world. Their mission is to provide you the most pure, and highest quality products beyond industry standards. And with their state-of-the-art manufacturing techniques, and stringent packaging quality control, we are proud to tell you that you are getting from the best. Let us support you take one step further to a healthier and a happier life.

Pros:

  • Non-GMO
  • No Gluten
  • No Soy
  • No Tree Nuts
  • No Artificial Colors
  • Strongly supports cognitive function, neuronal membranes, 
  • Improves mental focus and attention
  • Adrenal support

Cons:

  • Not suitable for children unless prescribed by doctor 

LongLifeNutri Uridine Monophosphate

LongLifeNutri Uridine Monophosphate

Why We Like It?

High potency levels, highly effective brain-boosting supplement 

The supplement is highly effective in improving brain function and overall cognitive health. One serving a day delivers necessary uridine for boosting neural health. 

Highlights:

  • Pure Uridine 300 mg
  • 120 Capsules per container
  • Vegan
  • Regularly tested and research verified
  • Special LongLifeNutri Pill Case
  • Made according to strict GMP USP USDA standards
  • Made in USA

Who Makes It?

LongLifeNutri is a brand owned by the company Carvalho Aleixo Inc, a family-run business based in Nevada selling natural dietary supplements, with custom formulas that would deliver the products with the highest quality available. It is all manufactured in FDA – registered and inspected, GMP – Certified state-of-the-art facilities in the US.

They not only sell the product on their own website, but also on Amazon in the USA and are also planning a rapidly expanding to Canada, UK, Germany and France.

Pros:

  • Gluten Free
  • Non GMO
  • Vegetable Cellulose (Capsule)
  • Support several cognitive enhancing properties for men and women
  • Magnesium Stearate from vegetable source
  • Help to perform at mental peak

Cons:

  • Not recommended for pregnant women and individuals under 18 years

Jarrow Formulas Uridine

Jarrow Formulas Uridine

Why We Like It?

Supports formation of Brain synapses and neuronal membranes, supports liver mitochondrial function and health

Highlights:

  • 250 mg
  • 60 capsules per container
  • Contains cellulose, magnesium stearate (vegetable source) and silicon dioxide 
  • Capsule consists of bovine gelatin (BSE-free).
  • Dietary Supplement

Who Makes It?

Jarrow Formulas’ mission is reflected in its motto ‘Superior Nutrition and Formulation”. Based in Los Angeles, California, USA and a formulator and supplier of superior nutritional supplements, the company was founded in 1977 and incorporated in 1988. Today it markets its products in the United States, Mexico, Canada and throughout the world.

Jarrow Formulas’ complete line of nutritional products including vitamins, minerals, probiotics, standardized herbal concentrates, amino acids, enzymes and enteral nutrition products, assure noth retailers and consumers of purity, value and potency when choosing these products.

The company is active in monitoring governmental regulatory affairs, which affect the nutritional industry and also vigorously promotes the rights of Americans to free access to dietary supplements. Jarrow Formulas funds research studies on important nutritional products to ensure that customers receive the full biological value of these products.

Pros:

  • Supports Formation of Brain Synapses and Neuronal Membranes
  • Supports Liver Mitochondrial Function
  • Can be taken on an empty stomach
  • Helps alleviate depression symptoms
  • Wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts free

Cons:

  • This product is labelled to United States standards and may differ from similar products sold elsewhere in its ingredients, labeling and allergen warnings

VitaMonk™ Uridine Monophosphate 

VitaMonk™ Uridine Monophosphate 

Why We Like It?

Promotes Synaptic Plasticity & Fluid Intelligence, greatly enhances choline

Highlights:

  • 350mg 
  • 60 capsules per container
  • Contains no wheat, gluten, corn, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts or egrInactive
  • Inactive ingredients include rice flour, vegetable capsule
  • Wheat, gluten, corn, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, artificial colors, artificial sweeteners, or preservatives. Inactive ingredients: rice flour, vegetable capsule
  • Formulated by licensed doctors
  • Manufactured in state-of-the-art facilities following strict GMP compliance standards

Who Makes It?

VitaMonk brings you the best quality health supplements available. The company opts for natural options when given the choice between natural and synthetic alternatives making most of their products completely natural. The top priority is placed on product purity and the quality of the research in verifying a compound as safe and effective. 

Pros:

  • No artificial fillers, 
  • No artificial sweeteners
  • No preservatives
  • No magnesium stearate
  • Works with Alpha GPC as the famous “Mr. Happy” stack.
  • Help facilitate memory, retention and overall mental performance
  • Promotes IQ, Fluid Intelligence & Synaptic Plasticity

Cons:

  • Side effects may include diarrhea

Absorb Health Uridine 

Absorb Health Uridine 

Why We Like It? 

Sensitizes the Brain to Choline

The supplement allows choline to increase synapse connection. 

Highlights:

  • 250mg each capsule
  • 100 capsules per container 
  • Cutting-edge supplement
  • Manufactured in GMP-Compliant Facilities

Who Makes It?

Absorb Health began in 2011 when Katrina, Josh Fulton’s wife, got sick. Josh began exhaustive research into natural methods that could mitigate and potentially cure this illness.

During his research, Josh realized that many natural health products could be brought to market more affordably, which would help bring optimal health within reach of more people.

This passion to help bring the highest quality of health to the most people was their motivation and they strive for excellent customer service, such as offering one day handling and a money back guarantee. They remain committed to affordable and reasonable prices so everyday people can have access to their products. 

Pros:

  • 100 capsules instead of 60 for a mere few more dollars
  •  Goes along with Alpha GPC

Cons:

  • The bottle does not say what form of uridine it is
  •  Not advisable if you have kidney problems.

Natural BioScience Uridine Monophosphate

Natural BioScience Uridine Monophosphate

Why We Like It?

Maximum strength uridine monophosphate

The optimal recommended dose of pure natural uridine is derived from the highest quality ingredients and gives maximum benefit for healthy cognitive function.

Monophosphate (UMP or 5′-uridylic acid), a naturally occurring nucleic acid, is crucial for many brain functions, including memory, learning, attention, focus and concentration

Highlights:

  • 350 mg
  • 60 capsules per container
  • Maximum strength uridine
  • Vegetarian capsules
  • Made in USA

Who Makes It?

The Natural BioScience brand was founded on the belief that natural is better. The company is inspired by a desire to improve people’s health, wellbeing and quality of life and are committed to providing their consumers with top quality supplements made with carefully selected and scientifically proven ingredients which must be derived from nature. Through their commitment to natural health the company makes every effort to ensure that their products are formulated to be close to the biological state of nutrients found in nature.

Pros:

  • Choline enhancer
  •  Increases the synthesis of phosphatidylcholine in the brain
  •  Pure uridine powder in capsules
  • Non-GMO 
  • No added gluten, soy, dairy,
  • tree nuts
  • No artificial colors or flavors

Cons:

  • Might cause dopamine crash

Absonutrix Uridine

Absonutrix Uridine

Why We Llke It?

Choline enhancer, great value

Highlights:

  • 500mg per capsule
  • 120 capsules per container
  • Capsule shell made from vegetable cellulose.
  • Made in USA

Who Makes It?

Absonutrix is a supplier of health and nutritional supplements for men and women interested in benefiting from the latest advancements in nutrition without sacrificing quality and performance.

Absonutrix is headquartered in North Carolina, U.S. and was formed in response to a glaring void in the nutritional and health products market. Every product the company sells is manufactured entirely within the U.S. with their suppliers having to  meet the company’s strict demands for quality before using their raw materials in the products the company makes.

The company is  dedicated to providing products manufactured from the finest ingredients, never settling for inferior, cheap, or second-rate suppliers. For anyone who cares about what goes into their bodies and are diligent when it comes to ensuring that they consume only the proper nutritional components, then the Absonutrix family of products is made for them.

Pros:

  • Vegetarian
  •  Encourages natural synthesis of citicoline
  •  Easy-to-take supplement

Cons:

  • Not to be consumed by pregnant or nursing mothers 
  • Individuals with preexisting conditions need to consult a doctor before consumption

Element Nutraceuticals Uridine Monophosphate

Element Nutraceuticals Uridine Monophosphate

Why We Like It?

Cardioprotective qualities, uridine 5-monophosphate disodium salt

Highlights:

  • 300 mg uridine per serving
  • 60 capsules per container
  • Active Ingredients include Uridine monophosphate
  • Other Ingredients include gelatin and rice flour

Who Makes It?

The team at Element’s ultimate goal is to promote optimal health with high quality, effective, affordable and “cutting edge” supplements. The team consists of athletes Lionel Gomez, Jordan Grant, Matt Mercado and Joel Agron. 

Pros:

  • Improvement of synaptic health and function
  • Has cardioprotective qualities
  • Helps to promote overall brain health and functionality
  • Helps to improve comprehensive health

Cons:

  • Should be taken by individuals with preexisting conditions 

Nootropics Depot Uridine Monophosphate

Nootropics Depot Uridine Monophosphate

Why We Like It?

Cognitive enhancer, choline precursor

Nootropics Depot offers 60ct or 120ct jars of high quality Uridine monophosphate capsules (Disodium Salt). Nootropics Depot’s Uridine monophosphate has been lab-tested and verified for both product purity and identity.

Highlights:

  • 250mg 
  • 120 count capsules per container
  • Active ingredient includes Uridine Monophosphate

Who Makes It?

Nootropics Depot features an extensive range of dietary supplements and nootropic compounds and offers the best nootropics and natural extracts from industry leading manufacturers including Nammex, Verdure Sciences, Embria Health Science, and Ixoreal Biomed.

The company provides a variety of dietary supplements and nootropic compounds in both capsule and powder forms, allowing one to develop the best nootropic stack.

From common cholinergics to whole fruiting body medicinal mushroom extracts and fish oil supplements, Nootropics Depot provides an extensive range of dietary supplements and nootropic compounds. 

When making a purchase from Nootropics Depot, a quality product that has undergone extensive testing for both purity and identity is ensured. Nootropics Depot routinely conducts in-house and third-party lab testing to ensure product authenticity and efficacy.

Pros:

  • Effective supplement at good value
  • Promote cognitive function
  • Supports healthy sleep patterns
  • Helps promote working memory
  • Supports neurotransmission
  • Promotes brain plasticity
  • Promotes verbal and logical memory

Cons:

  • Not suitable for pregnant women
  • Not suitable for children under 18 years

Benefits Of Uridine Monophosphate Supplement

Uridine supplements provide a long range of benefits including- 

  • Acting as a cognitive enhancer
  • Promoting creativity and positive mood
  • Improving memory retention
  • Helping in bipolar disorder and depression
  • Bettering the mitochondrion working
  • Condensing ache and tenderness
  • Reducing daydreaming, amnesia (uridine monophosphate anxiety)
  • Increasing concentration and focus
  • Increasing gray matter in the brain 
  • Improving spatial working memory
  • Significantly reducing nerve pain.
  • Aiding in sleep
  • Improving alertness 
  • Elevating dopamine levels 
  • Lowering cortisol levels 

Possible Side Effects Of Uridine Supplements  

In some cases, individuals consuming uridine supplements might face the following side effects- 

  • Slow rate of bone development
  • Possible chances heart illness
  • Queasiness and diarrhea 
  • Itchiness 
  • Skin breakouts

FAQ

  • What is Uridine good for?

Uridine is one of the building blocks of RNA. And its function is to store memories. By taking a uridine supplement helps to increase the levels of RNA in your brain.

It can help memory enhancement, mental performance, remove anxiety

  • What is uridine monophosphate used for?

It escalates neuroplasticity as well as synaptogenesis by raising erudite phosphatidylcholine concentration to help create dendrite membranes.

  • What foods contain Uridine?
    • Tomatoes (0.5 to 1.0 g uridine per kilogram dry weight)
    • Brewer’s yeast (1.7% uridine by dry weight)
    • Broccoli Green fresh
    • Offal (liver, pancreas, etc.)
    • Walnuts.
    • Sugarcane extract.
  • Does uridine increase dopamine?

Yes, It does. Uridine works with CDP Choline stimulate the development of new dopamine receptors in the brain by activating D1 and D2 receptor signaling.

How To Take Uridine Monophosphate?

  • On its own: 500mg-1000mg of Uridine per day has been demonstrated to have cognitive-enhancing effects.
  • Combined with a Choline supplement: If you combine it with a Choline source (Alpha GPC or CDP Choline), it’s a good idea to match the dosage. e.g. 500mg CDP Choline + 500mg Uridine.
  •  Knowing your limits: Too much Uridine can cause diarrhoea and induce fevers.
  • Don’t drink too much coffee: Some users report that drinking high amounts of coffee with Uridine can cause irritability.

Conclusion

Uridine occurs naturally in living cells, after being produced by the liver. Dietary sources include beer (highest content), baker’s yeast, liver, pancreas, cruciferous vegetables, and breastmilk. The problem with uridine from food sources is that most of it never makes it from the digestive system to the brain, thus the need for supplementation. In supplementation, the phosphate group increases the bioavailability and helps it to cross the blood-brain barrier and works by being a precursor of brain synapses and nerve cell membrane phospholipids, enhancing cholinergic functions of the brain and lastly by supporting the liver and mitochondria. Uridine Monophosphate supports mitochondria by taking part in the conversion of galactose into glucose and protects the muscles and brain from inflammation and reduces pain by inhibiting leukocyte adhesion and accumulation of pro-inflammatory cytokines. These boosts assist the brain and neural system to function at its peak and also to maintain physical and mental health. Overall, uridine supplements are necessary to maintain cognitive, mental and neutral health for adults and senior citizens. 

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